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PF-05085727 at) TFA analogs of clinical stage anti-cancer

SKU: 33291165245

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Description

analogs of clinical stage anti-cancer small molecule ONC201

InChiKey: SVDWBHHCPXTODI-QIWYXCRTSA-N

Smiles: CC1(C)C[C@H]2C3=CC[C@@H]4[C@@]5(C)CC[C@H](O)[C@@](C)(CO)[C@@H]5CC[C@@]4(C)[C@]3(C)C[C@H](O)[C@]2(C[C@@H]1O)CO

Formula: C21H23N7OS

PF-05085727 at) TFA analogs of clinical stage anti-cancerPF 05085727 is a potent, selective and brain penetrant inhibitor of cGMP dependent PDE2A (IC50=2 nM). PF 05085727 inhibits PDE2A >4,000 fold selectivity over PDE1 and PDE3 11. Product information CAS Number: 1415637 72 7 Molecular Weight: 413. 40 Formula: C20H18F3N7 Chemical Name: 4 [4 (azetidin 1 yl) 1 methyl 1H pyrazolo[3,4 d]pyrimidin 3 yl] 1 methyl 5 [4 (trifluoromethyl)phenyl] 1H pyrazole Smiles:

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